Purify pharma- and natural extract compounds with cGMP-compliance
Liquid-based Centrifugal Partition Chromatography.
The GMP rCPC is RotaChrom’s liquid-liquid centrifugal partition chromatography (CPC) platform, designed to adhere to Pharma-GMP regulations.
Chromatography From Research to Industry.
Effortless scale-up from mg to kg/day to promote continuous production of APIs and macromolecules by liquid-liquid based centrigugal partitional chromatography (CPC). Select between lab-scale, pilot-scale, industrial-scale purification, or continuous manufacturing.
Purification Without Silica Gel
Versatile Purification Systems for a Wide Range of COIs
Purify macromolecules, peptides, nucleotides, steroids, stereoisomers, high or low polar compounds, drug-like compounds, and natural compounds.
Whether it's separation, isolation or remediation, the CPC’s extremely flexible and powerful solvent recycling system can be optimized to handle all of them according to the client request.
Bespoke Design for Pharma
No two Partners are the same. Chromatographic challenges and goals, and facilities are all individual and unique, and cannot be handled by generic “cookie cutter” solutions.
RotaChrom’s team can help its partners benefit from bespoke and custom-made purification solutions. Our team will ensure that the device the Partner receives is optimized so they can achieve maximum extraction.
The equipment's GMP qualification comes with Eudralex Vol. 4., FDA 21 CFR part 11 requirements, FDA 21 CFR 177.2600 certificates, AISI 316L SS with EN 10204 3.1. material certificates which is a must for pharmaceutical production.
Contact Us and Keep Learning.
Are you're ready to learn more about CPC technology, or see what are its applications? Please complete the form below, and we provide you a free GMP compliance guide for the RotaChrom's rCPC device.
rCPC Datasheet
The table below shows the performance and data of the rCPC, highlighting its maximum capacities.
Centrifugal Partition Chromatography
Centrifugal partition chromatography (CPC) is a liquid-liquid chromatographic technique, in which separation occurs between two immiscible liquid phases. Both the mobile and stationary phases are liquids, and the liquid stationary phase is immobilized by a strong centrifugal force. The solute’s retention depends simply on the liquid-liquid partition coefficient (Kd).
RotaChrom engineers designed the rCPC platform for pilot-scale purification tasks within a laboratory environment. It is ideal for all batch sizes, smaller or larger, or campaign type of research work, and continuous-batch production.
RotaChrom brings industrial-scale CPC solutions to businesses, researchers, CROs and CDMOs
What you have seen so far is just the tip of the iceberg.
If you'd like to dive deeper, please fill in the form above, and grab your free copy of RotaChrom's 'Advanced Chromatography' white paper. The paper covers 4 in-depth chapters about CPC and LLC.
RotaChrom Technologies developed the world’s first industrial scale centrifugal partition chromatography technology solution. These liquid chromatography machines revolutionized purification by providing innovative, sustainable, and efficient industrial scale LC-CPC chromatography to customers all over the world in various industries, including pharmaceutical, nutraceutical and botanical extracts.
RotaChrom’s proven GMP compliant CPC designs are effective solutions when looking for a high-purity, high-capacity, cost-effective and environmentally conscious solution. RotaChrom, with its in-house research laboratory employing world class PhD chemists, engineers and leading business professionals on multiple continents, is the best partner in purification.
Our portfolio includes several products, which can help you scale your business from research to industry. Select between lab scale, pilot scale or industrial scale purification:
- The rCPC platform for pilot-scale purification tasks within a laboratory environment. It is ideal for all batch sizes, smaller or larger, or campaign type of research work, and continuous-batch production.
- The iCPC platform, which is the largest commercially available centrifugal partition Chromatography instrument in the world. It is designed for industrial-scale purification projects in continuous batch operation mode.